Artefill is a filler that is effectively permanent due to the fact that the body cannot degrade it. It is composed of tiny microspheres in a suspension of bovine collagen. The collagen gets degraded over time but the microspheres remain and induce an inflammatory response by the body which deposits new collagen around it.
Because the results of Artefill depend on each individual's response to it, there is a certain amount of unpredictability. It is therefore prudent to initially under correct with artefill and use it in stages until the desired outcome is achieved.
Like most of the other fillers, Artefill is only FDA approved for injection into the nasolabial folds. Like all the other fillers, practitioners can use it in off label ways and inject it anywhere else they deem to be safe. That is where different doctors might have varying viewpoints as to where it is safe to inject.
The only places I would inject Artefill are in the nasolabial folds, bridge of the nose, high cheek bone area, and prejawl sulcus. All these places are conducive to deep injections on or close to the bone. The deeper the material is injected the less likely it is to cause troublesome lumps or other issues.
Because Artefill contains bovine collagen, a skin test is needed about a month prior to administration of Artefill to make sure you do not have an allergy to it. This is done for free in our office.
By Dr. Gal Aharonov